Thou Wilt Remember Us. Sacred Song

'Thou single wilt prove none': Counting, Succession and Identity in Shakespeare's Sonnets

Whither art thou, SCN10A, and what art thou doing?

Since its initial cloning in 1992, SCN5A (Nav1.5) has become known as “the” cardiac sodium channel.1 SCN5A encodes a tetrodotoxin (TTX)-resistant channel that is responsible for the inward sodium current (INa), which initiates the cardiac action potential. Its RNA and protein expression dominate the sodium channel landscape in the ventricle, atrium, and specialized conduction system. Mice heter...

Thou shalt not kill.

Section 241(b) and s. 14 of the Criminal Code unjustifiably infringe s. 7 of the Charter and are of no force or effect to the extent that they prohibit physicianassisted death for a competent adult person who (1) clearly consents to the termination of life and (2) has a grievous and irremediable medical condition (including an illness, disease or disability) that causes enduring suffering that ...

Metastasis: Wherefore Arf Thou?

The small GTP-binding protein Arf6 is known to be an important regulator of the actin cytoskeleton and of cell motility associated with metastasis. A recent study identifies yet another role for Arf6 in metastasis - as a regulator of plasma-membrane-derived microvesicle release.

Cyst, what art thou?

A 51-year-old woman, with a medical history of abnormal Pap smears, extended menstrual cycles, and Barrett’s esophagus, underwent an upper gastrointestinal endoscopic ultrasound for abnormal findings on a computed tomography scan. The ultrasound characterized a peripherally calcified, multicystic, and septated lesion that was close to both the pancreatic tail and the upper pole of the left kidn...